• He was apprenticed to an engraver and later studied at the "Society of Arts'.
• He worked as an engraver in Lausanne for a short time, then went on an Alpine expedition with Horace-Bénédict de Saussure; making sketches.
• In 1786, members of the Society, impressed with his work, recommended that he go to study in Paris and offered a scholarship.
• While there, he attended the École des Beaux-Arts, where he studied with Nicolas de Launay.
• Some of his paintings were purchased by Empress Maria Feodorovna and the former Empress, Joséphine de Beauharnais.
• In 1812, he was awarded a gold medal at the Salon.
• His son was the well-known illustrator and cartoonist, Rodolphe Töpffer, who is sometimes called the "father of the comic book".